Paediatric Clinical and Molecular Research (NUS)

Unit Code

01806

Department/Institution Offering Unit

Department of Pediatrics
National University of Singapore
Level 4 National University Hospital
5 Lower Kent Ridge Road
SINGAPORE 119074

web: www.med.nus.edu.sg/paed/

Unit Points

Research Points: 100

Coursework Points: 0

top of page

Contacts

Unit Coordinator/s:

A/Prof Samuel Chong
PhD, FACMG ( USA )
Department of Pediatrics
Yong Loo Lin School of Medicine
National University of Singapore
5 Lower Kent Ridge Road
SINGAPORE 119074

tel: +65 6772 4152
fax: +65 6779 7486
email: paecs@nus.edu.sg

top of page

Overall Objectives

• provide an introduction to the process and practice of research in the area of paediatric health
• encourage a broad understanding of the role of research in the development of clinical practice
• ensure a critical understanding of biomedical literature

top of page

Content

Coursework: N/A, However, students will be encouraged to audit NUS-organized courses that may be relevant to their research project.

Research:

Clinical Research

• Prevalence of uveitis in Asian patients with juvenile chronic arthritis.
• Improving dialysis outcomes in children and adolescents.
• Ambulatory blood pressure changes in children, adolescents and young adults with diabetes mellitus and its correlations with albuminuria

Clinical/Laboratory Research

• Shellfish allergy in the tropics and cross-reactivity with dust mite.
• Genetics of idiopathic nephrotic syndrome.
• Immunopathogenesis of nephrotic syndrome.
• The role of polymorphisms of the Multi-drug resistance-1 (MDR-1) gene and early response to therapy in childhood acute lymphoblastic leukaemia.
• Genetic determinants for neutropaenic sepsis in children with leukaemia.
• Gut microflora patterns in allergic and non-allergic children.
• Genetics of pre-eclampsia / pregnancy-induced hypertension.

Laboratory Research

• Novel strategies for single cell preimplantation genetic diagnosis.
• Universal aneuploidy analysis in preimplantation genetic screening.
• Transposon technology for transgenesis and gene discovery.
• Novel molecular diagnostics for dynamic mutation disorders.
• Determining the SCN5A haplotype frequencies in the Singaporean population and their association with sudden cardiac death.
• Mutation screening of the serum amyloid protein A gene for genetic variants associated with dyslipidaemia and atherosclerosis

top of page

Assessment Breakdown

Research Component: 100 points
Research Report (up to 10,000 words): 75%
Oral presentation: 12.5%
Supervisor's Evaluation: 12.5%

Coursework Component: 0 points
N/A

top of page

Student Numbers

Number of places available:
3

Prospective students please note: to be eligible for any overseas AMS unit, you must have attained an aggregate of at least 70% in the University of Melbourne medical course.